Is Rejuran Painful? Numbing, Injection Experience and Aftercare

October 25, 2026
Blog cover image for Is Rejuran Painful? Numbing, Injection Experience and Aftercare with a model portrait on a soft pink background

Why people ask whether Rejuran hurts

Rejuran is one of the most requested skin booster injections in Korea, and it is also one of the treatments people ask about most nervously. The reason is simple: Rejuran is delivered through many small injections across the face rather than one or two injection points. Patients who have read reviews online often see words like "stinging" and "bumpy" and want to know what the experience is really like before they book.


The honest answer is that most people describe Rejuran as uncomfortable rather than very painful, and that the level of discomfort depends on the injection technique, the areas treated, how well numbing cream is applied and your own sensitivity. This guide explains what to expect at each step, from numbing to the first few days of aftercare, so you can plan your visit calmly.


How numbing works before Rejuran

At most Korean clinics, Rejuran begins with a topical anaesthetic cream. The process usually looks like this:


  • Cleansing. Your makeup and sunscreen are removed so the numbing cream can be absorbed evenly.
  • Application. A layer of numbing cream is spread over the areas that will be injected, typically the cheeks, forehead and sometimes the area around the eyes.
  • Waiting time. The cream is left on for a period so it can take effect. Many patients use this time to relax or review the treatment plan.
  • Removal and disinfection. The cream is wiped off and the skin is disinfected before injections begin.


Numbing cream reduces the sharp sensation of the needle, but it does not make the area completely numb. You will usually still feel pressure and a mild sting as the product enters the skin. If you know you are sensitive to pain, mention this during your consultation so the doctor can discuss ways to make the session more comfortable.


What the injection experience feels like

Rejuran is a polynucleotide-based product, and its texture is slightly thicker than some hydrating boosters. Because it is placed in the superficial layers of the skin, the injections tend to create small raised bumps that look a little like mosquito bites. This is expected and is part of how the product is distributed.


During the session, patients commonly report:


  • A quick pinch with each injection. The needle itself is very fine, so the pinch is brief.
  • A stinging or pressure feeling. This comes from the product being placed under the skin, and it fades quickly after each injection.
  • Areas that feel more sensitive. Skin near the nose, upper lip and around the eyes is often more sensitive than the outer cheeks.
  • A short overall treatment time. The injection part itself usually takes a relatively short time for a full face, though numbing adds to the total visit length.


You can ask the doctor to pause briefly at any time. A calm, steady pace often makes the experience easier.


Aftercare in the first few days

Most of what people notice after Rejuran is visible rather than painful. Here is what is common in the days after treatment:


  • Small bumps. The raised injection points generally settle within the first day or so, though this varies.
  • Redness and mild swelling. These are common and usually short-lived.
  • Possible small bruises. Bruising can happen with any injection, especially if you bruise easily.
  • Tenderness when touching the skin. Light tenderness may last a short time.


General aftercare advice often includes avoiding heavy makeup on the day of treatment, skipping saunas, intense exercise and alcohol for a short period, keeping the skin clean and using gentle skincare and sunscreen. Avoid rubbing or massaging the treated area unless your doctor tells you otherwise. Your doctor will give you specific instructions, and if you notice anything unusual, such as increasing pain, spreading redness or signs of infection, contact the clinic or a doctor promptly.


Planning Rejuran during a trip to Busan

If you are visiting Busan, it helps to plan Rejuran early in your stay rather than the day before an important event or photo session. That gives the injection bumps and any redness time to settle. At Daybeau Clinic Seomyeon, Rejuran 2cc is listed at 139,000 KRW as a first-visit price, VAT excluded (10% VAT is added at payment), checked October 2026. You can see all listed treatments on our price list and learn more on our Rejuran page.


Your doctor will check whether Rejuran suits your skin at consultation, and results and comfort vary from person to person. If Rejuran does not seem like the right fit, the doctor may discuss other skin boosters instead.


Frequently asked questions

Is Rejuran more painful than other skin boosters?

Many patients find Rejuran slightly more noticeable than very fluid hydrating boosters, because of its texture and the superficial injection technique. Experiences vary, and numbing cream helps most people tolerate it well.


Can I go out in public right after Rejuran?

Yes, most people can go about their day, but small bumps and redness may be visible for a short time. Many visitors schedule the treatment on a day without important plans.


Should I take painkillers before my appointment?

Do not take any medication before treatment without checking with a doctor first, as some medicines can affect bruising. Tell the doctor about everything you take during the consultation.


Is Rejuran safe during pregnancy?

Cosmetic injections are generally postponed during pregnancy and breastfeeding. Please consult a doctor and mention your situation at the consultation.


Curious about Rejuran in Seomyeon? Book a consultation or message us on WhatsApp with your travel dates and questions.

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