Rejuran Aftercare: Managing Injection Bumps, Redness and Swelling

Why Rejuran leaves bumps in the first place

Rejuran is a skin booster made from polynucleotides (PN), injected into the skin to support repair and improve texture, hydration and fine lines. Unlike a filler designed to stay in place and add volume, Rejuran is placed in many tiny deposits close to the surface across the face.

Those small deposits are the reason Rejuran is famous for its temporary bumps. Each injection point leaves a little raised bead of product under the skin, so straight after treatment the face can look like it has a pattern of small blisters or mosquito bites. This is expected and is not a sign that anything went wrong. Knowing the normal timeline makes the aftercare much less stressful.

What is normal after Rejuran

Reactions vary with technique, the amount injected and your skin, but a common pattern looks like this:

Raised bumps. Visible straight away. For many people they flatten noticeably within several hours and mostly settle within a day or two, though some can be felt for a little longer.
Redness. Pinkness around the injection points is common for the rest of the day and may last into the next.
Mild swelling. Slight puffiness, especially under the eyes or on the cheeks, can appear the next morning.
Pinpoint marks or small bruises. Tiny needle marks are normal. Some people develop small bruises, which can take a week or so to fade.
Tenderness. The skin may feel sore to touch for a day or two.

Aftercare for bumps, redness and swelling

Your doctor will give specific instructions. Commonly recommended aftercare includes:

Leave the bumps alone. Do not press, massage or try to flatten them. They settle on their own as the product spreads and absorbs.
Cool gently. A clean cool pack wrapped in a cloth, applied for short periods, can ease redness and swelling. Avoid putting ice directly on skin.
Keep the face clean. Avoid touching the injection points with unwashed hands. Clinics often suggest skipping makeup for the rest of the day.
Use simple skincare. A mild cleanser and plain moisturiser are best for a day or two. Pause retinoids, exfoliating acids and scrubs until the doctor says otherwise.
Avoid heat. Saunas, jjimjilbang, hot baths and intense workouts are usually avoided for a day or two, as heat can increase redness and swelling.
Limit alcohol. Alcohol may worsen flushing and bruising, so many people skip it on the day of treatment.
Sleep slightly elevated. An extra pillow the first night may help reduce morning puffiness.
Protect from the sun. Use sunscreen once allowed, and a hat outdoors.

What is not normal

Serious complications from skin boosters are uncommon, but you should contact the clinic or a doctor if you notice:

Increasing pain or swelling. Symptoms that get worse after the first couple of days rather than better.
Signs of infection. Warmth, spreading redness, pus, or fever.
Persistent lumps. Firm bumps that remain for weeks or appear later.
Unusual skin changes. Blistering, a dusky or blotchy colour change, or an allergic-type reaction such as widespread itching or hives.

If you are already home, a local doctor can examine you. Sending photos to the clinic that treated you also helps them advise.

Planning Rejuran around your trip

Because bumps and pinpoint marks are visible for the first day, many visitors book Rejuran for an afternoon or evening and keep the rest of the day quiet. If you have important photos, leave at least a few days, and more if you bruise easily. Rejuran is also often given as a series, so ask the doctor whether a single session during your visit makes sense for your goals.

At Daybeau Clinic Seomyeon, Rejuran 2cc is listed at 139,000 KRW for the first visit. Prices are VAT excluded (10% VAT is added at payment) and were checked in October 2026. See the Rejuran page, the wider skin boosters overview and the full price list for other options.

Frequently asked questions

How long do Rejuran bumps last?

For many people they flatten within several hours to a day, although some can be felt for a few days. If firm lumps persist for weeks, contact the clinic.

Can I wear makeup after Rejuran?

Clinics commonly suggest waiting until the next day so the injection points can close. Follow the timing your doctor gives you.

Does Rejuran hurt?

Numbing cream is usually applied first. Many people still find it one of the more noticeable skin boosters because of the number of injection points. Tolerance varies.